Biotech & Health

23andMe updates its ancestry reports, but they’re still not perfect

Comment

23andMe, co-founded by CEO Anne Wojcicki, has deployed its latest update, featuring interactive ancestry details, cultural insights about food, art and language, and the option to order a physical ancestry book. Starting today, customers will be able to see more granular ancestry results from more than 1,000 regions, as well as 33 population-specific pages about cultural information.

Before this update, 23andMe simply said I was 12 percent British and Irish. Now, it’s able to break down where in the U.K. my ancestors likely lived. 23andMe, however, was not able to detect more granular data in Ireland.

It was also unable to detect additional evidence in Nigeria, where 23andMe says 25.2 percent of my ancestry comes from. That’s likely because, even though 23andMe has made efforts to grow the number of African and African-American people in its data set, it’s still lacking. Though, it’s worth noting no ancestry service has it all.

“The odds of receiving more granular results from a particular region (in your particular case, Ireland or Nigeria) depends on how much Nigerian DNA someone has and how many individuals are in the 23andMe reference dataset,” 23andMe Ancestry Group Product Manager Robin Smith told TechCrunch. “The reference dataset is continuously growing, and customers should be seeing even more refined ancestry results later in the year.”

Generally speaking, customers who share exact matches between their DNA and reference individuals from a particular region could potentially see granularity in regions of Anambra, Edo, Imo, Lagos and Ogun State in Nigeria, 23andMe spokesperson Christine Pai told TechCrunch.

It’s worth noting Ancestry says just 1 percent of my DNA comes from Nigeria and that the bulk of my African ancestry comes from Cameroon and Congo. But when I first signed up for Ancestry, the company said 39 percent of my ancestry came from Nigeria. This is all to say that these tools are imperfect and always subject to change. And, depending on where the bulk of your ancestry comes from, it may change dramatically.

“I’m not surprised you’ll get different results from different companies,” Dr. Jennifer Raff, Assistant Professor in the Department of Anthropology at the University of Kansas told TechCrunch back in September. “They have their own proprietary info based on those samples. If one of them has lots of individuals from a particular region and the other company does not, you’re more likely to show up as having ancestry from that region whereas if the other company doesn’t have that data represented in their database, it’s going to show up as a different population.”

This is problematic, given many people turn to these DNA testing tools to figure out more about who they are and where they come from. I’ll keep this brief, but I was pretty frustrated when I went from thinking I was very Nigerian (39 percent, according to Ancestry) to barely Nigerian (about one percent, also according to Ancestry) to then again a fair amount of Nigerian (25 percent, according to 23andMe).

“This is a problem and it’s one we need to educate people about — that your genetic ancestry is not your identity,” Dr. Raff said. “Also, those numbers really reflect what is in their database, and what’s in the database is largely reflective of genetic variations we see in present-day populations. That doesn’t necessarily mean it’s reflecting your actual ancestors.”

I asked Dr. Raff if DNA testing is just a load of crock, but she said it’s not.

“It’s not complete bullshit but there’s also a lot of uncertainty there,” she said. “We [humans] like definitive answers. We’re trying to use this as a tool for exploring our past. We like to have definite answers when we’re doing these explorations, but unfortunately, it’s not there yet.”

But that’s not entirely the fault of 23andMe and Ancestry. In order to be as accurate as humanly possible, these companies would need to sequence every person on the planet. That’s not currently feasible, so in the meantime, Ancestry points to its confidence levels.

“We take this pretty seriously and we do want people to understand what is something they can put money in the bank on, and what they should take with a grain of salt,” Ancestry Chief Scientific Officer Catherine Ball told TechCrunch back in September.

She added that Ancestry tries to be transparent about confidence levels. And, in Africa specifically, “it’s one of our most exciting opportunities and greatest challenge” due to the enormous amount of genetic diversity on the continent.

Additional reporting by Sarah Buhr.

More TechCrunch

Jasper Health, a cancer care platform startup, laid off a substantial part of its workforce, TechCrunch has learned.

General Catalyst-backed Jasper Health lays off staff

Live Nation says its Ticketmaster subsidiary was hacked. A hacker claims to be selling 560 million customer records.

Live Nation confirms Ticketmaster was hacked, says personal information stolen in data breach

Featured Article

Inside EV startup Fisker’s collapse: how the company crumbled under its founders’ whims

An autonomous pod. A solid-state battery-powered sports car. An electric pickup truck. A convertible grand tourer EV with up to 600 miles of range. A “fully connected mobility device” for young urban innovators to be built by Foxconn and priced under $30,000. The next Popemobile. Over the past eight years, famed vehicle designer Henrik Fisker…

11 hours ago
Inside EV startup Fisker’s collapse: how the company crumbled under its founders’ whims

Late Friday afternoon, a time window companies usually reserve for unflattering disclosures, AI startup Hugging Face said that its security team earlier this week detected “unauthorized access” to Spaces, Hugging…

Hugging Face says it detected ‘unauthorized access’ to its AI model hosting platform

Featured Article

Hacked, leaked, exposed: Why you should never use stalkerware apps

Using stalkerware is creepy, unethical, potentially illegal, and puts your data and that of your loved ones in danger.

12 hours ago
Hacked, leaked, exposed: Why you should never use stalkerware apps

The design brief was simple: each grind and dry cycle had to be completed before breakfast. Here’s how Mill made it happen.

Mill’s redesigned food waste bin really is faster and quieter than before

Google is embarrassed about its AI Overviews, too. After a deluge of dunks and memes over the past week, which cracked on the poor quality and outright misinformation that arose…

Google admits its AI Overviews need work, but we’re all helping it beta test

Welcome to Startups Weekly — Haje‘s weekly recap of everything you can’t miss from the world of startups. Sign up here to get it in your inbox every Friday. In…

Startups Weekly: Musk raises $6B for AI and the fintech dominoes are falling

The product, which ZeroMark calls a “fire control system,” has two components: a small computer that has sensors, like lidar and electro-optical, and a motorized buttstock.

a16z-backed ZeroMark wants to give soldiers guns that don’t miss against drones

The RAW Dating App aims to shake up the dating scheme by shedding the fake, TikTok-ified, heavily filtered photos and replacing them with a more genuine, unvarnished experience. The app…

Pitch Deck Teardown: RAW Dating App’s $3M angel deck

Yes, we’re calling it “ThreadsDeck” now. At least that’s the tag many are using to describe the new user interface for Instagram’s X competitor, Threads, which resembles the column-based format…

‘ThreadsDeck’ arrived just in time for the Trump verdict

Japanese crypto exchange DMM Bitcoin confirmed on Friday that it had been the victim of a hack resulting in the theft of 4,502.9 bitcoin, or about $305 million.  According to…

Hackers steal $305M from DMM Bitcoin crypto exchange

This is not a drill! Today marks the final day to secure your early-bird tickets for TechCrunch Disrupt 2024 at a significantly reduced rate. At midnight tonight, May 31, ticket…

Disrupt 2024 early-bird prices end at midnight

Instagram is testing a way for creators to experiment with reels without committing to having them displayed on their profiles, giving the social network a possible edge over TikTok and…

Instagram tests ‘trial reels’ that don’t display to a creator’s followers

U.S. federal regulators have requested more information from Zoox, Amazon’s self-driving unit, as part of an investigation into rear-end crash risks posed by unexpected braking. The National Highway Traffic Safety…

Feds tell Zoox to send more info about autonomous vehicles suddenly braking

You thought the hottest rap battle of the summer was between Kendrick Lamar and Drake. You were wrong. It’s between Canva and an enterprise CIO. At its Canva Create event…

Canva’s rap battle is part of a long legacy of Silicon Valley cringe

Voice cloning startup ElevenLabs introduced a new tool for users to generate sound effects through prompts today after announcing the project back in February.

ElevenLabs debuts AI-powered tool to generate sound effects

We caught up with Antler founder and CEO Magnus Grimeland about the startup scene in Asia, the current tech startup trends in the region and investment approaches during the rise…

VC firm Antler’s CEO says Asia presents ‘biggest opportunity’ in the world for growth

Temu is to face Europe’s strictest rules after being designated as a “very large online platform” under the Digital Services Act (DSA).

Chinese e-commerce marketplace Temu faces stricter EU rules as a ‘very large online platform’

Meta has been banned from launching features on Facebook and Instagram that would have collected data on voters in Spain using the social networks ahead of next month’s European Elections.…

Spain bans Meta from launching election features on Facebook, Instagram over privacy fears

Stripe, the world’s most valuable fintech startup, said on Friday that it will temporarily move to an invite-only model for new account sign-ups in India, calling the move “a tough…

Stripe curbs its India ambitions over regulatory situation

The 2024 election is likely to be the first in which faked audio and video of candidates is a serious factor. As campaigns warm up, voters should be aware: voice…

Voice cloning of political figures is still easy as pie

When Alex Ewing was a kid growing up in Purcell, Oklahoma, he knew how close he was to home based on which billboards he could see out the car window.…

OneScreen.ai brings startup ads to billboards and NYC’s subway

SpaceX’s massive Starship rocket could take to the skies for the fourth time on June 5, with the primary objective of evaluating the second stage’s reusable heat shield as the…

SpaceX sent Starship to orbit — the next launch will try to bring it back

Eric Lefkofsky knows the public listing rodeo well and is about to enter it for a fourth time. The serial entrepreneur, whose net worth is estimated at nearly $4 billion,…

Billionaire Groupon founder Eric Lefkofsky is back with another IPO: AI health tech Tempus

TechCrunch Disrupt showcases cutting-edge technology and innovation, and this year’s edition will not disappoint. Among thousands of insightful breakout session submissions for this year’s Audience Choice program, five breakout sessions…

You’ve spoken! Meet the Disrupt 2024 breakout session audience choice winners

Check Point is the latest security vendor to fix a vulnerability in its technology, which it sells to companies to protect their networks.

Zero-day flaw in Check Point VPNs is ‘extremely easy’ to exploit

Though Spotify never shared official numbers, it’s likely that Car Thing underperformed or was just not worth continued investment in today’s tighter economic market.

Spotify offers Car Thing refunds as it faces lawsuit over bricking the streaming device

The studies, by researchers at MIT, Ben-Gurion University, Cambridge and Northeastern, were independently conducted but complement each other well.

Misinformation works, and a handful of social ‘supersharers’ sent 80% of it in 2020

Welcome back to TechCrunch Mobility — your central hub for news and insights on the future of transportation. Sign up here for free — just click TechCrunch Mobility! Okay, okay…

Tesla shareholder sweepstakes and EV layoffs hit Lucid and Fisker